Lag 1-8 är klara för 8-delsfinal. Lag 9-16 spelar dubbelmöte mot ett lag 17-24 där vinnarna går till 8-delsfinal
| Hemmalag |
Poängsortera |
Champions 24/25 |
omg |
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| Ajax 0 (-6) | | Inter 0-2 | 25/11 | Benfica | 28/1 | Olympiacos | 5/11 | Galatasaray |
| Arsenal 6 (4) | 26/11 | Bayern | 21/10 | Atletico | | Olympiacos 2-0 | 28/1 | Kairat |
| Atalanta 3 (-3) | 9/12 | Chelsea | | Brugge 2-1 | 22/10 | Slavia | 21/1 | Bilbao |
| Atletico 3 (3) | 26/11 | Inter | | Frankfurt 5-1 | 28/1 | Bodö | 4/11 | Union |
| Barcelona 3 (0) | | PSG 1-2 | 9/12 | Frankfurt | 21/10 | Olympiacos | 28/1 | Copenhagen |
| Bayern 6 (6) | | Chelsea 3-1 | 22/10 | Club Brugge | 9/12 | Sporting | 21/1 | Union |
| Benfica 0 (-2) | 28/1 | Real M | 5/11 | Leverkusen | 10/12 | Napoli | | Qarabag 1-2 |
| Bilbao 0 (-5) | 10/12 | PSG | | Arsenal 0-2 | 28/1 | Sporting | 22/10 | Qarabag |
| Bodö 2 (0) | 20/1 | Man City | 25/11 | Juventus | | Tottenham 2-2 | 4/11 | Monaco |
| Brugge 3 (2) | 5/11 | Barcelona | 10/12 | Arsenal | 28/1 | Marseille | | Monaco 4-1 |
| Chelsea 3 (-1) | 25/11 | Barcelona | | Benfica 1-0 | 22/10 | Ajax | 21/1 | Pafos |
| Copenhagen 1 (-2) | 21/10 | Dortmund | | Leverkusen 2-2 | 20/1 | Napoli | 26/11 | Kairat |
| Dortmund 4 (3) | 28/1 | Inter | 25/11 | Villarreal | 10/12 | Bodö | | Bilbao 4-1 |
| Frankfurt 3 (0) | 22/10 | Liverpool | 26/11 | Atalanta | 28/1 | Tottenham | | Galatasaray 5-1 |
| Galatasaray 3 (-3) | | Liverpool 1-0 | 21/1 | Atletico | 22/10 | Bodö | 25/11 | Union |
| Inter 6 (5) | 9/12 | Liverpool | 20/1 | Arsenal | | Slavia. 3-0 | 5/11 | Kairat |
| Juventus 2 (0) | | Dortmund 4-4 | 21/1 | Benfica | 5/11 | Sporting | 10/12 | Pafos |
| Kairat 0 (-8) | | Real M 0-5 | 20/1 | Brugge | 9/12 | Olympiacos | 21/10 | Pafos |
| Leverkusen 2 (0) | 21/10 | PSG | 1/10 | Villarreal | | PSV 1-1 | 10/12 | Newcastle |
| Liverpool 3 (0) | 4/11 | Real M. | | Atletico 3-2 | 26/11 | PSV | 28/1 | Qarabag |
| Man City 4 (2) | 5/11 | Dortmund | 25/11 | Leverkusen | | Napoli 2-0 | 28/1 | Galatasaray |
| Marseille 3 (3) | 21/1 | Liverpool | 5/11 | Atalanta | | Ajax 4-0 | 25/11 | Newcastle |
| Monaco 1 (-3) | | Man City 2-2 | 28/1 | Juventus | 22/10 | Tottenham | 9/12 | Galatasaray |
| Napoli 3 (-1) | 28/1 | Chelsea | 4/11 | Frankfurt | | Sporting 2-1 | 25/11 | Qarabag |
| Newcastle 3 (3) | | Barcelona 1-2 | 21/10 | Benfica | 21/1 | PSV | 5/11 | Bilbao |
| Olympiacos 1 (-2) | 26/11 | Real M | 20/1 | Leverkusen | 4/11 | PSV | | Pafos 0-0 |
| Pafos 1 (-4) | | Bayern 1-5 | 5/11 | Villarreal | 28/1 | Slavia | 26/11 | Monaco |
| PSG 6 (5) | 4/11 | Bayern | | Atalanta 4-0 | 26/11 | Tottenham | 28/1 | Newcastle |
| PSV 1 (-2) | 28/1 | Bayern München | 9/12 | Atletico | 21/10 | Napoli | | Union 1-3 |
| Qarabag 6 (3) | 5/11 | Chelsea | 21/1 | Frankfurt | 10/12 | Ajax | | Copenhagen 2-0 |
| Real 6 (6) | 10/12 | Man City | 22/10 | Juventus | | Marseille 2-1 | 20/1 | Monaco |
| Slavia 1 (-3) | 21/1 | Barcelona | 4/11 | Arsenal | | Bodö 2-2 | 25/11 | Bilbao |
| Sporting 3 (2) | 20/1 | PSG | 26/11 | Brugge | 22/10 | Marseille | | Kairat 4-1 |
| Tottenham 4 (1) | 20/1 | Dortmund | | Villarreal 1-0 | 9/12 | Slavia | 4/11 | Copenhagen |
| Union 3 (-2) | 21/10 | Inter | 28/1 | Atalanta | 9/12 | Marseille | | Newcastle 0-4 |
| Villarreal 1 (-1) | 21/10 | Man City | | Juventus 2-2 | 20/1 | Ajax | 10/12 | Copenhagen |